Representative Publications

2.     Cui, G., Dong, Q., Duan, J., Zhang, C., Liu, X. #, and He, Q #. NC2 complex is a key factor for the activation of catalase-3 transcription by regulating H2A.Z deposition. Nucleic Acids Research. 2020 Sep 4;48(15):8332-8348. (#Corresponding author)

3.     Liu, X.*, Chen, A.*, Caicedo-Casso, A., Cui, G., Du, M., He, Q., Lim, S., Kim, H.J., Hong, C.I., and Liu, Y. FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora. Nature Communications. 2019,10, 4352. (* Co-first author)

4.     Cao X*, Liu X*, Li H, Fan Y, Duan J, Liu Y and He Q. Transcription factor CBF-1 suppresses frequency transcription by modulating the proper binding of WHITE COLLAR complex in Neurospora. PLoS Genetics. 2018 Sep; 14(9): e1007570. (* Co-first author)

5.     Liu X, Dang Y, Matsu-Ura T, He Y, He Q, Hong CI, Liu Y. DNA replication is required for circadian clock function by regulating rhythmic nucleosome composition. Molecular Cell. 2017 Jul 20;67(2):203-213.e4. (Highlighted by Nature Reviews Molecular Cell Biology)

6.     Sun G*, Zhou Z*, Liu X*, Gai K, Liu Q, Cha J, Kaleri FN, Wang Y, He Q. Suppression of WHITE COLLAR-independent frequency transcription by histone H3 lysine 36 methyltransferase SET-2 is necessary for clock function in Neurospora. Journal of Biological Chemistry. 2016 May 20;291(21):11055-63. (* Co-first author)

7.     Liu X, Li H, Liu Q, Niu Y, Hu Q, Deng H, Cha J, Wang Y, Liu Y, He Q. Role for protein kinase A in the Neurospora circadian clock by regulating White Collar-independent frequency transcription through phosphorylation of RCM-1. Molecular and Cellular Biology 2015 Jun;35(12):2088-102.

8.     Zhou Z*, Liu X*, Hu Q*, Zhang N, Sun G, Cha J, Wang Y, Liu Y, He Q. Suppression of WC-independent frequency transcription by RCO-1 is essential for Neurospora circadian clock. PNAS. 2013 Dec 10;110(50):E4867-74. (* Co-first author)

Representative Pictures

Fig.1 Coupling of circadian clock and cell cycle

DNA replication is required for circadian clock function by regulating rhythmic nucleosome composition.  Liu X, et al., Molecular Cell. 2017. (Highlighted by Nature Reviews Molecular Cell Biology)

Fig. 2 FRQ-CK1 interaction underlies the period and temperature compensation of circadian rhythms

FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora. Liu X, et al, Nature Communications. 2019

FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock. Hu Y, et al, mBio. 2021