Prenyltransferases in fungal genomes, for the biosynthesis of natural products and as biocatalysts in the chemoenzymatic synthesis

报告题目：Prenyltransferases in fungal genomes, for the biosynthesis of natural products and as biocatalysts in the chemoenzymatic synthesis

 

报告人：Prof. Shuming Li

 

报告人单位：Institut für Pharmazeutische Biologie und Biotechnologie， Philipps-Universit？t Marburg

 

报告时间：2014年7月29日10 时—11 时30分

 

报告地点：A102

 

主持人：尹文兵 报告人简历： Shu-Ming Li, born in Henan, China, in 1961, is full professor for Pharmaceutical Biology and director of the Institute of Pharmaceutical Biology and Biotechnology at the Philipps-University in Marburg, Germany. From 1979 to 1986, he studied pharmacy and finished his master thesis on isolation of plant natural products at the Beijing University Health Science Center. He received his PhD degree in 1992 from the Rheinische Friedrich-Wilhelms-University in Bonn, Germany. The topic of his dissertation was identification of biologically active substances from algae. He spent then three years (1992-1995) for post-doc training in Freiburg and Tübingen and worked on shikonin biosynthesis in cell cultures. The research interests of Prof. Li as assistant professor at the University Tübingen from 1996 to 2006 were biosynthesis of antibiotics in bacteria, especially aminocoumarins in Streptomyces. From 2006 to 2008, Prof. Li has served as an associate professor for Pharmaceutical Biology at the Heinrich-Heine-University in Düsseldorf. His professorship in Marburg began after that in 2008. The current research interests of Prof. Li began 2005 and focus on the genomics of the biosynthesis of secondary metabolites in fungi, especially on prenylated indole alkaloids and prenyltransferases of the DMATS superfamily. Li′s group was one of the first research groups, which have identified biosynthetic genes for secondary metabolites from fungal genome sequences by bioinformatic methods and proven their function by molecular biological and biochemical approaches. Prof. Li is a member of the German Pharmaceutical Society, the Society for Medicinal Plants and Natural Product Research, the General and Applied Microbiology, Association of Professors in Germany. He is also a member of state examination commission of German pharmacists.